Pharmacologically active and innovative substances as those derived from biotechnology (peptides, proteins, genes) have generally low stability, poor absorption and transport to the active site, as well as subject to rapid cleavage – with consequent induction of severe adverse reactions. In order to overcome these problems, vectors drugs like nanoparticles have been receiving special interest for innovative therapies of severe skin disease – Muco-cutaneous Leishmaniasis and cell carcinoma as examples.

This project aims at the development of new therapeutic systems for charging small peptides for the treatment of various skin diseases of endemic etiology.

UFP participants:
– Prof. Doctor Eliana B. Souto
– Ms. Ana Sofia Macedo (doctoral student in Biotechnology and Health)
– Ms. Vânia Vieira (doctoral student in Biotechnology and Health)

Submitting entity:
– Fundação Ensino e Cultura Fernando Pessoa

Other institutions:
– University of Trás-os-Montes e Alto Douro
– Institute for Pharmacy, Freie Universität Berlin (Germany)
– Universidad Nacional de Quilmes (Argentina)

Project supported by:
European Commission – EULANEST